The DaMBIC is equipped for imaging of samples ranging from single molecules and cells to tissue and small animals. Image modalities include:
- Confocal laser microscopy, “in vitro environment” confocal imaging and upright confocal microscopy
- STED (STimulated Emission Depletion microscopy)
- CARS (Coherent anti-Stokes Raman microscopy)
- Spinning disk microscopy (live cell imaging)
- TIRF (Total Internal Reflection Fluorescence microscopy)
- FLIM (Fluorescence Lifetime IMaging)
- FCS (Fluorescence Correlation Spectroscopy)
- Two-photon microscopy
- RICS (Raster Imaging Correlation Spectroscopy)
- AFM (Atomic Force Microscopy)
- IVIS Spectrum
- PET CT (Positron Emission Tomography, Computed Tomography)
Which microscope to choose:
For fast imaging you probably need a widefield system.
Confocal and spinning disk, are ideal to image samples that are thicker than 10 um.
For very thick samples, the multiphoton might be needed.
TIRF systems are used to image the area of the cell close to the coverslip.
If the resolution needed is higher than 200 nm, you will need super resolution like STED.